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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '289454f1afb7b0ee7f424319660d16b054ba40be82bb0be16e692e37d4c7a5ba' 
  AND token = '1Va2y7ZYLCDvelunCS1G3nB/MZCqnrdoM4hOW8MuiJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}