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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ee7397144e41ef0618788f6cba4b9c4c32efb28da4cb2d0352a409e1d59813' 
  AND token = 'SdmtemEx7PtVcxcuHLm9QU7YR2iS7iCizMUe7Z7fz64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}