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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2b2d6ea2114d70b385417a2517310acb385f990b92df9d8a68889239325f1ca' 
  AND token = '0/f8iGfYuzHppUQ3M97Gm3jUsh9IgXQ2VsfkTdUj3oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}