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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '495dad0cb7371b6376c4f9d2a831f4b0e8deb7da483a3adb3c760927675e594c' 
  AND token = 'Am4yLBxwdzCh+35/01OnF81eE1xNjC0TMbUbIqcjFkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}