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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccd29ceb9f24772f1d1087804de6871d9a1ee232d6d3407b7aed42afc17d5a25' 
  AND token = 'yY3Hf/7DNaBme878xO4H6NfNZRdyNW9oaIcigk77pZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}