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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b717bcb7e27525975a10657869a8e305c2df36e2b4c49245b1be1111ffef54a' 
  AND token = 'RM7SP3uUA4IwZH028mc4dipKilzbhS0H8lo3kY4MZoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}