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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aa7ef0ab63349c503cd619031abce588e2253cbed50a55e39df12f1c176a25c' 
  AND token = 'RnTmumTHfE6YFFkTqmA0tlq5VBOJnZdxol08eldH6fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}