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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d29533fffb02d6a8b19486afc53906daa6fe3627245962941747564639f706f' 
  AND token = 'dmAxhgTeCxl8h3J18UnMJdIQHYMywkczch8A4LxZgIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}