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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd395b073737f423e6afdc35aabef06564baf25d0e53b3693b6b084ee0b65534a' 
  AND token = 'L3mm4QO/PsxYvgSll9hD7ch2c8+nV9wZyMgjvpEuwcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}