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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e15478677413b08692099f29d9bc72e35e5c85f69f51208227f396c0a6e257ad' 
  AND token = 'zJySkDsnnb/c7N06eyxSiGEC7kurCBsRxTr0BCynJBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}