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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fdc038cb4beed89ada97b080ff5e71e4dcff3c50a9f6954e41b94792cc77a12' 
  AND token = 'EN3NyOG+pMpWo4RBq2nvDF2Fvej6BxTb79Pjs1HpbSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}