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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dfc19b82ef425d632cf07e2a97a704dcaa1be6802acb42a7ec862bcf5d4ac27' 
  AND token = 'TJQ/ECZDrxGmW3GeGmQtSwrotfD6j6Cgt42tY/qxp8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}