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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7b578758b8e4c0dde299cf620e4ce9f130e94093b2e3da7f312b0018be7c6b' 
  AND token = 'dvzHVP7we01DIMQpBnCnGqxdQVV5oyZ8JimB7Ppy6bQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}