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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246510f9702b219402303e517638ce13ba5ed3ff8fe233dbdfa78741c511ccbc' 
  AND token = 'Faeq0jw3T6KUdYcqjy60IC2d/XRdt76we9AUsbA2HVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}