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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c19f93f4039383b6261dfd7209751ba4fff40624c182c4492d624e721638d6f2' 
  AND token = 'U272GCMhqyuabZRAN4NDKewqOrTx6V3uN54FLRSUHCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}