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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aa6beba7d93878d102481baaeb46b6c3b355f22321cc83f5c6d49ef8db73386' 
  AND token = '+kGJSIELV8TtZvh+fQHbgPn5dqGgVvGcfvxAROpc8ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}