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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b5faf3d0b8b203742f9cbdd0dc110d384c8d6326c12e36aad36b12e30734ea5' 
  AND token = 'In2Xf8WAA6Vgx6LtF1rcWzX6qBOK5xfUoppWeaYnTzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}