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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae3b0b9d2615278fb3efeba1a1a06335811bc16e22b9bf9eacdef1343803ca8c' 
  AND token = 'PRO38rWfnMT/wxUXNNgvSH+yP9nZzdtID85xoyE6dvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}