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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ab7863935bc2274af6869b138d842263855e3486960a5b97c425b6f3b9b8e14' 
  AND token = 'uxyXwkAT+qkfgd1KJ0A6PMxd+oiK6v1GomCd9Kqw4UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}