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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e754a79e69fc0664458e69b73a45f4453187a677bf49d06484b2ef3b3f5a546' 
  AND token = 'NN0UI4vkaOJe2m8lJzqJCD0CY4BVMcQ7xVHLd7RvhSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}