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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bbe378519ee36d1054aac71d75344f03df9626940b59b0c6b18e51622156374' 
  AND token = '/dNipE5lcg1igxkQMV7uz4JexWfFfaxN4JSerdkijlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}