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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae61645af2f09f055bd61ee1a24d8b09b942829d741a545a670b9d91ae21da4' 
  AND token = 'UslnbULrUNUOXSA29trv+uWRkQvU8oK709veQ11C/uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}