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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '516818d39baa9cf92b2049af62deb14f6b5a07e0a65aff7197c3e46a9021eed6' 
  AND token = 'TgtqiDicOeqm9kOhVSZzi+s6fS83QtfZXNs9lJK8nxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}