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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a037389097e748db3d268d03bd8ab2d183b713d64dd36c8749d77a7aefbf1aa' 
  AND token = 'ofV1j2A66spXoXUPpJQNSg1XTQLFogp6qBcawsH/4PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}