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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b6cc28d0ea138591d9a7a4066102158490b42a141ab14639a1c9654ab485df3' 
  AND token = 'W83y+FElW/Sx0kiDaVQ6FM9qcaIb+rf/pq1x7ldVoVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}