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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bd1355ea6076c7df1efb72e7bde8bfc31cfd250ce951bcf3b97205e955f1c5c' 
  AND token = '2aH2YeCKUCEGy6pDD13lp0/BeNjBKj1TOKtj4kjBgmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}