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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1384bbb61044fc5ec6614ebfd4662672fc62d3dccaefab10f31ad819ded14c5e' 
  AND token = 'VWgl1rc1EMw3/nZb65w1gVUs8P6DRQpPLIRwzoW1Q3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}