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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0259393f304f990409cb0cb2ab6a19ee6054e9f35a9d990045e9d857120e0b' 
  AND token = 'u646EzgG+UjbdzfgKaGRoYLVPEUsFxJg/Yd0VL82p3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}