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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550e8f368a33672e5123cb4640f5d8076ddadd14ce2eb0dfa85a32c21faac962' 
  AND token = 'LkEGuXPU6FJv++Lsk+0VK5JMQAiCFsPd2647+daVFkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}