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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a4b28b948b94cd03bc9d1b901bf0537c1c8279c3cb42f5a7f7e04668262e73e' 
  AND token = 'isZKElGkxrceTToHFR4e/czBqlLufZDq2pU1fUuTPCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}