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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b618c3104aad448304c3866b9e7ab7708083eb425ce97c856ec6945d2dd8a1' 
  AND token = 'nD8UCqacjyHr+0HCTVuhq+TovT6RHg6BZC5oRki4uqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}