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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cc4c38e130985d35580d28b7dee36a8bae4d21f4cb38502c5954c722694e4ca' 
  AND token = 'megndPEnPv0PmSmNRH4iN9Qk0FZzTLNY9OBME/8Yco0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}