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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b3dca1900eac65f8daa237dde08b72c6d23feda8e7e1f58ab2a8f0a076aa5aa' 
  AND token = 'TMoHKXiQG94PGO9ZJ17d/XCvjvsqGMjTbA2HriQOFuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}