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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18fc3c8df164802ce27feb780af4a247647539915342af1dbe63b0b3a620d08' 
  AND token = 'IuEKSiNweCVXfQXmQljAK3DZLo7I95xc2kFWpc8VwQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}