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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66d87fc3c56097a67df28177d7d2e51f38eff7510f44e1c5626bea40de002ad3' 
  AND token = 'edb9fS8qS7llI5kdIBAm0RlNLFNhNqus7xolNCF8XwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}