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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5804390100ca58a2a8bdd5658c8b462d04ac2525c1b63360c51d7bfac590a7f' 
  AND token = 'R65ZNYhPOclq6jGC8ssSAQZ9/Zua/Q4FkCbji91Hej4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}