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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebe4957ee8eb66a3265d9ed1a724dba11cfa0eb7581407317aca1d02785fe172' 
  AND token = 'NGNPftvSkJfrI/m/NhRmbMtf2tX4slDA2SQUNaJHZRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}