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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48afa5ae5e8f088454388b4f4a148d1658ecd9eea9d173b6cf2a15c3145d715d' 
  AND token = 'MrFZ0HfjbM46pJzZ01TL3OYEm/IQApRqe3Ot87SAjpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}