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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c57fe9115e47b0f157ead68b658b6df41f05a17d1e06e30bcdf6d60d182f22f6' 
  AND token = 'QL50fL4Q+V6e05TCsFdYPLLr+auLeTZx1YxrLW1uXIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}