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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817224f6d9328920cc8a2fc234d892203b79b80d09894914c9d15fe3e161c53e' 
  AND token = 'OIo+qaIl1rXAoicrJ1fRkCV3JXiNgVsZd6ScnEuuCkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}