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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdd289df56a5510c7648357bb17ec8d78d0a44ac5c190c0c7dd70c99cc9a00d3' 
  AND token = 'TA6Zzaxk7d3zp5GuL0hKVxKLjNu6KIbRWjL62OPPuQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}