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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3de0f2e5d8dcd3ba3ebe6d401ac3d84cd253be63953dd985bb0db029bfc5436' 
  AND token = '0pliiYn0y+MqtwKqgG/MF6uS3pt7O7g3QC1oOupTdLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}