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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da04a80e0d6bcbe8289a286a754fd0cf9daf5972143db430fbb46b9c1499dfe9' 
  AND token = 'l1NGO2Sg5Y7gExN9CTQ4+UPjS59WzqXeqfvl2MxdzXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}