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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d8e4147d75a24465f04f54dda6cf47c8e02621f9f80a7951bc6f4351ec120d5' 
  AND token = 'CstqG2rZQo+vw2Oj8+yoqraFyu4DR8sj45pE4eAw7Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}