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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22afebe1af974d60c3127c13473817a3681a8820d43b677a9ccd2be7a28aacbd' 
  AND token = 'qZF3iSzuFenm3B20ADLDr8hLM+bFS6wtE9EQVqpq6LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}