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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b646b188ebcb9677a14ebba63739fab3d9f6501797c06617cd35e500998a59f' 
  AND token = 'ABVdxbqWcFYUfBFTdysdTWd7i3uRv72C56uXfCsKb0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}