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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc70642dd66fd6817385d22631ce72415c9814a0b81dcb5f5dff30d8b444701' 
  AND token = '34SeAgNy8PoeB5nfjbUqCNmcfZO6+lQvxotZXtwefPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}