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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e27b54ce7c5e9873921e35e596e51aa61ab8c740f5c4e039024b31b011d81f53' 
  AND token = '7kFnEEz+KdN9mUBj2gYSwKR4rOYT49F0cjyMu74hE5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}