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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b77f10109f0f43060aaee89547339f7f1f81adc217a84a41df96b9446a9023' 
  AND token = 'x0fh8mF4rhktgRMGl+WEi8265noICt2IQXnzYdfeG/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}