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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dbe1eb9e9e9965bc53a4070a1492da12ec47e4f2698adbe47a28ad77303b647' 
  AND token = 'AGu+uNM0X4Sagen1gaO6Ahk/Ml5HvEdPHIJRQk3t76g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}